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In a very current analyze, we documented the identification as well as the characterization of a fresh atypical opioid receptor with exceptional detrimental regulatory Houses to opioid peptides.1 Our final results showed that ACKR3/CXCR7, hitherto generally known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a wide-spe